Hi Mukesh!
 
Generally, it is advised that you show a strong interest in working in the specific lab you are applying to in your initial email. This is best done by looking up or reading through the lab’s past published research and explaining why you are interested in the scientific field they study, making sure to reference the lab’s works and accomplishments. That way, they know you understand and like the research topic they focus on. I would also suggest including some information about you, whether that’d be a resume/list of relevant classes you have taken/special computer skills/past research experience (if applicable) along with your intended major and potential career path (i.e. if you’re premed, you can mention that!). All in all, the most important thing is to show genuine interest in their specific lab, especially in your first email!
 
Hope that helps! Let us know if you have any other questions.
Leen, PMH Advising Manager